Police said the accident took place on NH-37 at Panbari when a bus carrying 30 passengers from Bokakhat to Guwahati collided with another multi utility vehicle with 21 passengers on their way from Nagaon to Jorhat.
Five passengers died on the spot while two others succumbed to their injuries on way to a hospital, they said.
Among the injured, 10 persons were admitted to Bokakhat Civil Hospital in critical conditions, hospital authorities said.